Vaccine

Polylactic

co

glycolic acid

 

#PLGA #

Nomisma Healthcare

 India

Poly(lactide-co-glycolide) (PLGA) is a well-established biodegradable polymer used in medical devices and drug delivery applications.

The isomer of Lactic acid

01

L-Lactide

D-Lactide

DL-Lactide

02

Molecular Weight

03

End Group

Acid- Terminired

Ester- Terminated

Composition of Lactide and Glycolide

04

75:25

50:50

85:15

80:20

90:10

10:90

Available varients

10kD to 120kD

PLGA  is used for the Control drug Delivery system in advance nano medicins.

Leuprolide Depot for 1 month is one of them.

Drug delivery

PLGA with Vitamin C and Vitamin E Nanoparticles use in Cosmetic products.

Cosmetic

PLGA  is used in Biodegradable orthopedic implants.

A biodegradable porous orthopedic screw is one of them.

Orthopedic Implants

Electrospun PLGA fiber sheets incorporating fluorescent nanosensors

Bio-sensor 

APPLICATION

Yellow Stairs

(Lactide: Glycolide) PLGA with different composition ratio used as APIs and Excipients in Advanced Drug Delivery formulation as Biodegradable Polymers also in Biopharmaceutical Process Development, NDDS, and Manufacturing of

the Controlled Release, Excipients like  Lactide, and Glycolide Polymers used in Liquid Dosage Forms, Materials Science  as Poly(Lactide-co-Glycolide) (PLGA) Copolymers, Polymer Science, Products for Sustained Drug Release Injectables

Poly(lactide-co-glycolide) (PLGA)

50:50 DL-PLG / 50:50 Poly(DL-lactide-co-glycolide) / 0.15 - 0.25 IV /Ester 

50:50 DL-PLG / 50:50 Poly(DL-lactide-co-glycolide) / 0.15 - 0.25 IV /Acid 

50:50 DL-PLG / 50:50 Poly(DL-lactide-co-glycolide) / 0.26 - 0.54 IV /Ester 

50:50 DL-PLG / 50:50 Poly(DL-lactide-co-glycolide) / 0.55 - 0.75 IV /Acid 

50:50 DL-PLG / 50:50 Poly(DL-lactide-co-glycolide) / 0.55 - 0.75 IV /Ester 

50:50 DL-PLG / 50:50 Poly(DL-lactide-co-glycolide) / 0.76 - 0.94 IV /Ester

50:50 DL-PLG / 50:50 Poly(DL-lactide-co-glycolide) / 0.95 - 1.20 IV /Ester

65:35 DL-PLG / 65:35 Poly(DL-lactide-co-glycolide) / 0.55 - 0.75 IV /Ester 

65:35 DL-PLG / 65:35 Poly(DL-lactide-co-glycolide) / 0.83 - 0.93 IV /Ester

75:25 DL-PLG / 75:25 Poly(DL-lactide-co-glycolide) / 0.15 - 0.25 IV /Acid 

75:25 DL-PLG / 75:25 Poly(DL-lactide-co-glycolide) / 0.55 - 0.75 IV /Ester 

75:25 DL-PLG / 75:25 Poly(DL-lactide-co-glycolide) / 0.70 - 0.90 IV /Acid 

75:25 DL-PLG / 75:25 Poly(DL-lactide-co-glycolide) / 0.80 - 1.20 IV /Ester 

85:15 DL-PLG / 85:15 Poly(DL-lactide-co-glycolide) / 0.55 - 0.75 IV /Ester 

85:15 DL-PLG / 85:15 Poly(DL-lactide-co-glycolide) / 0.76 - 0.85 IV /Ester 

55:45 DL-PLG-Glu / 55:45 Poly(DL-lactide-co-glycolide) Glucose Star Polymer / 0.40 - 0.60 IV

 

Poly lactide (PLA)

DL-PL / Poly(DL-lactide) / 0.26 - 0.54 IV /Ester 

DL-PL / Poly(DL-lactide) / 0.16 - 0.25 IV / Acid 

DL-PL / Poly(DL-lactide) / 0.55 - 0.75 IV /Ester 

L-PL / Poly(L-lactide) / 0.15 - 0.35 IV /Ester 

L-PL / Poly(L-lactide) / 0.90 - 1.20 IV /Ester / ACL Scrow

Polyglycolic acid (PGA)

Polyglycolic acid for surgical suture

PGA / Poly(2-hydroxyacetic acid) / 1.2 IV / Acid

Conducting polymers

Polyaniline

At Nomisma health care, Polyaniline is a regular product in Portfolio and it is having a better quality profile against the commercially available and can be made available in small or Bulk Quantities depending upon the requirement. 

 

Lactide

L-Lactide CAS 4511-42-6

D(+)-lactide - CAS 13076-17-0

D(+)-lactide - CAS 13076-17-0

DL-Lactide CAS 95-96-5

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